Introduction to Telomeres and Aging
What are telomeres?
Telomeres are essential structures located at the ends of our chromosomes. They act as protectors, preventing chromosomes from being damaged or fusing with each other. However, with each cell division, telomeres shorten, eventually leading to cellular aging.
The relationship between telomere length and age
As we age, the length of our telomeres decreases. This reduction has been associated with various age-related diseases and a shorter life expectancy. Therefore, maintaining telomere length is essential for a healthy life.
Fagron TeloTest: A Revolutionary Tool
Analysis Process
Fagron TeloTest analyzes quantitative data associated with telomere length. These data are obtained from a specific laboratory test performed on DNA extracted from a buccal swab.
Algorithm and Patient Questionnaire
Based on the results, the Fagron TeloTest algorithm consults a patient questionnaire and related tables to block or classify various APIs and nutraceuticals.
Nutraceuticals and APIs: Benefits and Relationship with Telomeres
Vitamin D3
Vitamin D3 has been shown to have a positive correlation with telomere length in humans. Furthermore, vitamin D3 supplementation has a positive effect on telomere length and significantly reduces overall mortality among older adults.
Folate (Vitamin B9)
Serum folate (Vitamin B9) concentrations have been positively related to telomere length. Furthermore, nutritional factors with antioxidant properties, such as folate, could act as modifiers of the associations between toxic metals and telomere length.
Cyanocobalamin (Vitamina B12)
Older men and women are prone to vitamin B12 deficiency. Vitamin B12 concentrations have been positively correlated with telomere length.
Vitamin C (Ascorbic Acid)
Vitamin C has been shown to have properties ranging from a simple antioxidant to a micronutrient capable of epigenetic regulation.
Vitamin E (Tocopherols, Tocotrienols)
The intake of vitamin E has a beneficial effect in the prevention and management of chronic diseases.
Resveratrol
Resveratrol is a natural phenol with a high antioxidant potential. In vitro experiments have shown that resveratrol increases telomerase activity and prevents senescence in human cells.
Acetylcysteine
Acetylcysteine is an established mucolytic and antidote for paracetamol poisoning. It may be effective in medical conditions associated with aging.
Astaxanthin
Astaxanthin is a red carotenoid with diverse biological activities. It has a strong antioxidant effect.
Omega-3
Omega-3 supplements have a significant beneficial effect in preventing cognitive decline in the elderly.
Turmeric
Turmeric is a plant with a long history of use in traditional medicine, especially to treat inflammatory conditions.
Pomage
Pomage is a substance isolated from the dry extract of Malus pumila with important antioxidant and anti-inflammatory biological activities.
Piperine
Piperine exerts anti-inflammatory, neuroprotective, cardioprotective and anticancer effects.
Miodesin™
Miodesin™ is a patented phytocomplex that has been shown to exert anti-inflammatory effects.
Pycnogenol®
Pycnogenol® is a French maritime pine bark extract with promising effects in improving various conditions.
Metformin
Metformin is a safe and effective glucose-lowering agent for the treatment of diabetes.
Testosterone
Testosterone is essential for men's health and well-being.
Cycloastragenol (TA-65)
Cyclastragenol is a triterpenoid saponin isolated from several species of legumes of the genus Astragalus.
SiliciuMaxTM
SiliciuMaxTM is an orthosilicic acid stabilized with maltodextrin.
Silymarin (SM)
SM is a standardized extract from the seeds of milk thistle, a medicinal plant.
Pinetonin™
Pinetonin™ is a phytocomplex obtained from a mixture of 3 essential oils.
Ginkgo Biloba
Ginkgo Biloba may play an important role in preventing the vascular aging process.
GreenSelect
GreenSelect is a purified extract of tea catechins enriched with a high concentration of epigallocatechin-3 gallate (EGCG).
Coenzyme Q10 (CoQ10)
CoQ10 is the third most consumed dietary supplement after fish oil and multivitamins.
Conclusion
Cellular health and telomere length are essential for a healthy life. Fagron TeloTest and the aforementioned nutraceuticals offer a promising solution to maintain and improve cellular health.
Frequent questions
- What is Fagron TeloTest? It is a tool that analyzes quantitative data associated with telomere length.
- Why is telomere length important? Telomere length has been associated with various age-related diseases and shorter life expectancy.
- What are nutraceuticals? They are products derived from foods that are used medicinally to provide health benefits.
- How can vitamin D3 help? Vitamin D3 has been shown to have a positive correlation with telomere length in humans.
- What is resveratrol and how can it help? Resveratrol is a natural phenol that has been shown to increase telomerase activity and prevent senescence in human cells.