The main ingredient of Colgenium is Colostrinin in the form of the patented COLOCO PRP® polypeptide, characterized by a high proline content (approx. 20%), which contributes to the high bioactivity and bioavailability of Colostrinin.
Colostrinin appears in colostrum, that is, in the first milk of mammals, which increases the ability of offspring to develop non-specific immunity. Colostrinin is found in colostrum in variable amounts depending on the phase of lactation. The highest level of these peptides is found in the colostrum secreted from the first to several dozen hours after calving. After that, its content in breast milk gradually decreases.
The COLOCO PRP® polypeptide is an extract of colostrum and its most valuable protein fraction with clinically proven properties.
Colostrinin may have an impact on the aging process, because by reducing the number of spontaneous and induced DNA mutations related to oxidative stress and mutations induced by UVA and UVB rays, it slows down the processes of aging and cell death cerebral.
It may also be an opportunity for people with Alzheimer's disease, which is one of the neurodegenerative diseases of the brain, because calostrinine slows down the process of accumulation of the negative effects of the destruction of nerve cells in the brain and the deposit of abnormal proteins, beta-amyloid, in them.
The composition of Colgenium has also been supplemented with synergistic action pyroxine, that is, vitamin B6, which participates in the metabolism of amino acids, fatty acids, carbohydrates, hormones and cholesterol, and in the synthesis of neurotransmitters, hemoglobin and fatty acids. Pyridoxine is necessary for the proper functioning of the nervous system, it is involved in the production of neurotransmitters such as serotonin, dopamine and norepinephrine. It affects blood pressure, muscle contractions and heart function, increases the body's resistance, as it participates in the formation of antibodies. Vitamin B6 deficiency causes an increase in homocysteine in the blood, which has the effect of contributing to free radical damage to blood vessel walls. Elevated levels of this amino acid are also one of the main risk factors for heart disease.