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Genetics and diabetes: what role does it play in its development?

06 Mar 2023
La genética y la diabetes: ¿qué papel desempeña en su desarrollo?

Diabetes is a metabolic disease that affects more than 460 million people worldwide. This pathology is characterized by a high concentration of glucose in the blood due to the lack or ineffectiveness of insulin, a hormone produced by the pancreas that allows the cells of the body to use glucose as a source of energy. The most common symptoms of diabetes are polyuria, polyphagia and polydipsia, known as "the 3 P rule", which makes the disease quickly diagnosed.

Diabetes is divided into three main types based on its cause. Type 1 develops when the immune system attacks the insulin-producing cells of the pancreas, causing a complete deficiency of this hormone. Type 2, by contrast, is the result of a combination of genetic and environmental factors, and occurs when the body is unable to use insulin efficiently, known as insulin resistance. Finally, gestational diabetes occurs during pregnancy and can go away after delivery, although it increases the risk of developing type 2 diabetes later in life.

Genetics play a critical role in the development of diabetes. Although it is known that the disease is due to the interaction between genetic and environmental factors, it has been shown that there is a heritability rate of up to 80% between siblings. This means that people who have a close relative with diabetes are at higher risk of developing the disease.

Knowledge of the genetic predisposition to suffer from diabetes can be very useful to prevent or delay the onset of the disease, since it makes it possible to identify people who have a higher risk of developing it. In addition, it can also make the diagnostic process easier, as doctors can be more attentive to symptoms and screen earlier than usual.

The tellmeGen Advanced DNA test is a very useful tool to obtain information about genetic predisposition to diabetes. This test analyzes more than 300,000 genetic variations and provides information on the risk of developing the disease, as well as advice on how to prevent it or delay its onset.

It is important to keep in mind that although genetics is a determining factor in the onset of diabetes, there are also many environmental factors that can influence its development. Lifestyle, diet and physical exercise are some of the factors that can influence the risk of developing the disease.

In conclusion, diabetes is a widespread metabolic disease throughout the world that is divided into three main types according to its cause. Genetics play an important role in the development of the disease, and knowing the genetic predisposition to suffer it can be very useful to prevent or delay its onset. The tellmeGen Advanced DNA Test is a very useful tool to obtain this information and take preventive measures to avoid diabetes. However, it is important to remember that diabetes is also

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